What is Humatrope (somatropin for injection)?

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Humatrope is a man-made form of human growth hormone. It was first approved in 1987 to treat children who are growing slowly because they do not make enough growth hormone on their own.

Humatrope is available in 6 mg, 12 mg, and 24 mg cartridges for use in a HumatroPen® injection device. Humatrope 72 iu is also available in vials for use with a syringe and needle.

Who is Humatrope for?

Humatrope is used to treat children who are short or growing slowly because they:

Do not make enough growth hormone on their own
Have Turner Syndrome
Have idiopathic short stature, which means they are shorter than 98.8% of other children of the same age and sex, are growing at a rate not likely to allow them to reach normal adult height, and for whom no other cause of short stature can be found
Have SHOX deficiency
Were born smaller than normal for the number of weeks of pregnancy and do not catch up in height by 2 to 4 years of age

Humatrope is used to treat adults who have growth hormone deficiency that began either in:

Adulthood (as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma); or
Childhood. Patients treated for growth hormone deficiency in childhood whose bones have stopped growing should be reevaluated to determine if they should continue growth hormone
How does Humatrope work?
Humatrope is a man-made form of growth hormone. Growth hormone is essential for growth—made by the pituitary gland (located at the base of the brain), then released into the bloodstream, where it travels to the body’s tissues. Here it stimulates production of another hormone important for growth, called insulin-like growth factor 1, or IGF-1. Growth hormone works to stimulate growth, in large part due to its effect in producing IGF-1.

What can I expect?

Although results may be different for everyone, Humatrope has data from clinical studies to help support treatment decisions. Throughout treatment, help your child remember that growth is a gradual process that takes time, even with treatment. Talk with your doctor about setting realistic expectations for your child’s treatment, and include your child in the conversation. Helping a child understand what to expect may help them stay motivated to continue therapy.

Where can I learn about safety?

Humatrope underwent studies that assessed safety and tolerability. When prescribing treatment for your child, your doctor is able to carefully consider the results of those studies by reviewing the Full Prescribing Information for Humatrope. You can also read through the Full Prescribing Information, as well as the Important Safety Information for Humatrope on this site. If you want help in understanding that information, or if you have specific questions about Humatrope safety and tolerability with your child in mind, please discuss them with your doctor.

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